
1-(4-Ethoxy-3-methoxyphenyl)propan-2-one synthesis
- Product Name:1-(4-Ethoxy-3-methoxyphenyl)propan-2-one
- CAS Number:126278-69-1
- Molecular formula:C12H16O3
- Molecular Weight:208.25
Yield:126278-69-1 79%
Reaction Conditions:
Stage #1: 2-chloro-propionic acid methyl ester;4-ethoxy-3-methoxybenzaldehydewith sodium methylate in methanol;toluene at 0 - 20; for 24 h;
Stage #2: with sodium hydroxide in toluene at 50;
Stage #3: with hydrogenchloride;water in toluene at 80 - 85; for 2 h;
References:
Lakó, ágnes;Mendon?a, Ricardo;Molnár, Zsófia;Poppe, László [RSC Advances,2020,vol. 10,# 67,p. 40894 - 40903]

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