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ChemicalBook CAS DataBase List 1-(5-hydroxy-2-nitrophenyl)ethanone
30879-49-3

1-(5-hydroxy-2-nitrophenyl)ethanone synthesis

3synthesis methods
Preparation by nitration of 3-hydroxyacetophenone,
with nitric acid (d = 1.4) in acetic acid, at 70° (31%), (15%)
with cupric nitrate in acetic acid–acetic anhydride mixture, between 12° and 15° (20%).
-

Yield:30879-49-3 44%

Reaction Conditions:

with acetic acid;potassium nitrate at 60; for 1.16667 h;Inert atmosphere;

References:

Wang, Jingjing;Chen, Weiqiang;Zuo, Sujing;Liu, Lu;Zhang, Xinrui;Wang, Jianhui [Angewandte Chemie - International Edition,2012,vol. 51,# 49,p. 12334 - 12338][Angew. Chem.,2012,vol. 124,# 49,p. 12500 - 12504,5] Location in patent:supporting information

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