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73261-84-4

1-(6-Chloroisoquinolin-2(1H)-yl)ethan-1-one synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / H2 / PtO2 / ethyl acetate / 1 h / 1034.3 Torr
2: 35 percent / AlCl3 / CH2Cl2 / 0.17 h / Ambient temperature

References:

Perchonock;Lantos;Finkelstein;Holden [Journal of Organic Chemistry,1980,vol. 45,# 10,p. 1950 - 1953]