ChemicalBook CAS DataBase List 1,7-Diphenyl-4-hepten-3-one

1,7-Diphenyl-4-hepten-3-one synthesis

9synthesis methods

Product Name:1,7-Diphenyl-4-hepten-3-one
CAS Number:79559-59-4
Molecular formula:C19H20O
Molecular Weight:264.3615

104-53-0
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41162-19-0 Synthesis

Dimethyl (2-oxo-4-phenylbutyl)phosphonate

41162-19-0
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79559-59-4
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Yield:79559-59-4 92%

Reaction Conditions:

Stage #1: dimethyl(2-oxo-4-phenylbutyl)phosphonatewith potassium carbonate in tetrahydrofuran at 20; for 0.666667 h;Inert atmosphere;
Stage #2: 3-phenyl-propionaldehyde at 40; for 12 h;

References:

Wang, Congcong;Zhang, Yu-Fang;Guo, Shimeng;Zhao, Quan;Zeng, Yanping;Xie, Zhicheng;Xie, Xin;Lu, Boxun;Hu, Youhong [Journal of Medicinal Chemistry,2021,vol. 64,# 2,p. 941 - 957]