(1-Benzyl-3-fluoro-3-piperidyl)MethanaMine synthesis

2synthesis methods

Product Name:(1-Benzyl-3-fluoro-3-piperidyl)MethanaMine
CAS Number:1185749-68-1
Molecular formula:C13H19FN2
Molecular Weight:222.3

3-Piperidinemethanamine, 3-fluoro-1-(phenylmethyl)-, 2,2,2-trifluoroacetate (1:1)

1204307-11-8
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(1-Benzyl-3-fluoro-3-piperidyl)MethanaMine

1185749-68-1
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Yield:1185749-68-1 82%

Reaction Conditions:

with sodium hydrogencarbonate in water;

References:

Van Hende, Eva;Verniest, Guido;Thuring, Jan-Willem;Macdonald, Gregor;Deroose, Frederik;De Kimpe, Norbert [Synlett,2009,# 11,p. 1765 - 1768] Location in patent:experimental part

3-Piperidinecarbonitrile, 3-fluoro-2-oxo-1-(phenylmethyl)-

1185749-64-7
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1185749-68-1
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References

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