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1-Bromo-2-(dimethoxymethyl)-4,5-dimethoxybenzene synthesis

3synthesis methods
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Yield:70461-33-5 100%

Reaction Conditions:

Stage #1: 2-bromo-4,5-dimethoxybenzaldehyde;trimethyl orthoformate;toluene-4-sulfonic acid in methanol; for 3 h;Heating / reflux;
Stage #2: with sodium methylate in methanol;

References:

WO2007/40240,2007,A1 Location in patent:Page/Page column 26