1-Bromo-3-(isopropylsulfanyl)benzene synthesis
- Product Name:1-Bromo-3-(isopropylsulfanyl)benzene
- CAS Number:70398-87-7
- Molecular formula:C9H11BrS
- Molecular Weight:231.15
6320-01-0
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$8.00/1g
75-26-3
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$10.00/10g
70398-87-7
10 suppliers
$133.33/0.25g
Yield:70398-87-7 100%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 20;
Steps:
al.1; az.1
Step 1 : 1-bromo-3-(isopropylthio)benzene2-Bromopropane (5.46 mL, 58.2 mmol) was added dropwise into a mixture of 3- bromothiophenol (6.29 mL, 52.9 mmol) and K2COs (10.96 g, 79.3 mmol) in anhydrous DMF (100 mL), and then stirred at RT overnight. The reaction mixture was diluted with water (200 mL) and extracted with TBE (3x150 mL). The combined organic layers were washed with brine, dried (MgS04) and concentrated under reduced pressure to give the title compound as a colourless oil (12.44 g, quantitative), used without further purification, UPLC/MS (max plot) 100%; Rt 2.23 min; ( S+) no signal.
References:
WO2012/155199,2012,A1 Location in patent:Page/Page column 86
75-30-9
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$15.00/1g
6320-01-0
177 suppliers
$8.00/1g
70398-87-7
10 suppliers
$133.33/0.25g
1073-06-9
421 suppliers
$6.00/10g
20607-43-6
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$161.00/10g
70398-87-7
10 suppliers
$133.33/0.25g