1-BROMO-4-FLUORO-2-ISOPROPOXYBENZENE synthesis
- Product Name:1-BROMO-4-FLUORO-2-ISOPROPOXYBENZENE
- CAS Number:610797-49-4
- Molecular formula:C9H10BrFO
- Molecular Weight:233.08
75-30-9
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$15.00/1g
147460-41-1
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$5.00/1g
610797-49-4
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$75.00/1g
Yield:610797-49-4 95%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 80; for 8 h;
Steps:
4
2-Bromo-5-fluoro-phenol Compound 4a (3.0 g, 15.7 mmol), 2-iodo-propane Compound 4b (4.0 g, 23.6 mmol), K2CO3 (3.3 g, 23.6 mmol) and DMF (50 mL) were heated and stirred at 80° C. for 8 hrs. The excess DMF was removed under reduced pressure and the white residue was mixed with AcOEt (100 mL), washed with water and dried (Na2SO4). The filtered dry solution was evaporated to provide 1-bromo-4-fluoro-2-isopropoxy-benzene Compound 4c (3.48 g, 95%) as a yellowish oil.
References:
US2006/217419,2006,A1 Location in patent:Page/Page column 35
75-26-3
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147460-41-1
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$5.00/1g
610797-49-4
34 suppliers
$75.00/1g
348-57-2
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67-63-0
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1036724-61-4
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610797-49-4
34 suppliers
$75.00/1g