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ChemicalBook CAS DataBase List (1-ETHYNYLCYCLOPROPYL)BENZENE
139633-98-0

(1-ETHYNYLCYCLOPROPYL)BENZENE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / diethyl ether; tetrahydrofuran / 2 h / 0 - 20 °C
2: pyridinium chlorochromate / dichloromethane / 12 h / 20 °C / Molecular sieve
3: potassium carbonate / methanol / 3 h / 20 °C

References:

COCRYSTAL DISCOVERY, INC.;LEE, Sam, Sk;SHEN, Wang;ZHENG, Xiaoliang;JACOBSON, Irina, C. WO2012/83105, 2012, A1