ChemicalBook CAS DataBase List 1-HYDROXYPYRENE

1-HYDROXYPYRENE synthesis

9synthesis methods

Product Name:1-HYDROXYPYRENE
CAS Number:5315-79-7
Molecular formula:C16H10O
Molecular Weight:218.25

78751-40-3
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Yield:5315-79-7 95.4%

Reaction Conditions:

with water;sodium hydroxide at 60;

Steps:

1.3 Preparation of 1-hydroxypyrene

1000 ml of water,80 g of sodium hydroxide (2 mol) and 245 g of acetoxypyrene obtained in Step 2 were added to a 2000 ml reaction flask,After the mixture is fully dissolved,The mixture was warmed to 60 ° C,After sufficient reaction (approximately 6 hours for this example)Cooling to about 30 ° C, and then dropping 500ml concentration of 35% concentrated hydrochloric acid,To be fully reacted,It will produce a large number of white solid,The mixture was filtered,dry,To give 196 g of solid 1-hydroxyprene as a white solid,The HPLC chromatogram of 1-hydroxypyrene shown in Figure 3 shows that the content of 1-hydroxypyrene is 99.28%The yield of 1-hydroxypyrene was 95.4%.

References:

CN105732331,2016,A Location in patent:Paragraph 0020

164461-18-1 Synthesis