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188998-38-1

1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[3,4-B]PYRIDINE synthesis

5synthesis methods
188998-35-8 Synthesis
Formamide, N-(4-formyl-1-methyl-1H-pyrazol-5-yl)- (9CI)

188998-35-8
3 suppliers
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1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[3,4-B]PYRIDINE

188998-38-1
4 suppliers
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Yield:-

Steps:

Multi-step reaction with 5 steps
1: tetrahydrofuran / 5 h / Ambient temperature
2: conc. aq. HCl / methanol / 2 h / Ambient temperature
3: 96.5 percent / H2 / 10percent Pd/C / tetrahydrofuran / 3 h / Ambient temperature
4: 51.9 percent / xylene / 4 h / Heating
5: 70.3 percent / LiAlH4 / tetrahydrofuran / 1.5 h / Heating

References:

Ohki, Hidenori;Kawabata, Kohji;Inamoto, Yoshiko;Okuda, Shinya;Kamimura, Toshiaki;Sakane, Kazuo [Bioorganic and Medicinal Chemistry,1997,vol. 5,# 3,p. 557 - 567]

62564-90-3 Synthesis
5-Amino-1-methyl-1H-pyrazole-4-carbaldehyde

62564-90-3
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1-METHYL-1H,4H,5H,6H,7H-PYRAZOLO[3,4-B]PYRIDINE

188998-38-1
4 suppliers
inquiry