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1-o-Tolyl-1H-pyrazol-5-amine synthesis

3synthesis methods
15001-09-9 Synthesis
ethyl 5-amino-1-(2-methylphenyl)-1H-pyrazole-4-carboxylate

15001-09-9
6 suppliers
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Yield:14678-98-9 75%

Reaction Conditions:

with hydrogenchloride in water; for 12 h;Reflux;

References:

Marinozzi, Maura;Carotti, Andrea;Sardella, Roccaldo;Buonerba, Federica;Ianni, Federica;Natalini, Benedetto;Passeri, Daniela;Rizzo, Giovanni;Pellicciari, Roberto [Bioorganic and Medicinal Chemistry,2013,vol. 21,# 13,p. 3780 - 3789]