1-Oxa-5-thia-S-indacene-4,8-dione synthesis
1synthesis methods
- Product Name:1-Oxa-5-thia-S-indacene-4,8-dione
- CAS Number:73540-69-9
- Molecular formula:C10H4O3S
- Molecular Weight:204.2
Yield:73540-69-9 60%
Reaction Conditions:
Stage #1: N,N-diethylfuran-3-carboxamidewith n-butyllithium in tetrahydrofuran;hexane at -78; for 0.333333 h;Inert atmosphere;
Stage #2: 3-thiophene carboxaldehyde in tetrahydrofuran;hexane at -78; for 2.25 h;Inert atmosphere;
Stage #3: with n-butyllithium in tetrahydrofuran;hexane at -78 - 20;Inert atmosphere;
References:
Aeschi, Yves;Li, Hui;Cao, Zhencai;Chen, Songjie;Amacher, Anneliese;Bieri, Nathalie;Oezen, Bilal;Hauser, Juerg;Decurtins, Silvio;Tan, Songting;Liu, Shi-Xia [Organic Letters,2013,vol. 15,# 21,p. 5586 - 5589] Location in patent:supporting information