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1001070-23-0

1H-Pyrrolo[2,3-b]pyridine, 6-bromo-1-(phenylsulfonyl)- synthesis

1synthesis methods
-

Yield: 95%

Reaction Conditions:

Stage #1:6-Bromo-1H-pyrrolo<2,3-b>pyridine with sodium hydride in tetrahydrofuran at 0; for 1 h;
Stage #2:benzenesulfonyl chloride in tetrahydrofuran at 0; for 1 h;Further stages.;

References:

Stoit, Axel R.;den Hartog, Arnold P.;Mons, Harry;van Schaik, Sjoerd;Barkhuijsen, Nynke;Stroomer, Cees;Coolen, Hein K.A.C.;Reinders, Jan Hendrik;Adolfs, Tiny J.P.;van der Neut, Martina;Keizer, Hiskias;Kruse, Chris G. [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 1,p. 188 - 193]