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ChemicalBook CAS DataBase List tert-butyl 4-(2-formyl-4-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate
1017782-93-2

tert-butyl 4-(2-formyl-4-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate synthesis

2synthesis methods
6361-21-3 Synthesis
2-Chloro-5-nitrobenzaldehyde

6361-21-3
284 suppliers
$6.00/5g

57260-71-6 Synthesis
1-BOC-Piperazine

57260-71-6
736 suppliers
$5.00/5g

tert-butyl 4-(2-formyl-4-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate

1017782-93-2
17 suppliers
inquiry

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Yield:1017782-93-2 100%

Reaction Conditions:

with potassium carbonate in N,N-dimethyl-formamide at 90; for 4 h;

References:

William, Anthony D.;Lee, Angeline C.-H.;Blanchard, Stéphanie;Poulsen, Anders;Teo, Ee Ling;Nagaraj, Harish;Tan, Evelyn;Chen, Dizhong;Williams, Meredith;Sun, Eric T.;Goh, Kee Chuan;Ong, Wai Chung;Goh, Siok Kun;Hart, Stefan;Jayaraman, Ramesh;Pasha, Mohammed Khalid;Ethirajulu, Kantharaj;Wood, Jeanette M.;Dymock, Brian W. [Journal of Medicinal Chemistry,2011,vol. 54,# 13,p. 4638 - 4658] Location in patent:experimental part

27996-87-8 Synthesis
2-Fluoro-5-nitrobenzaldehyde

27996-87-8
180 suppliers
$5.00/1g

57260-71-6 Synthesis
1-BOC-Piperazine

57260-71-6
736 suppliers
$5.00/5g

tert-butyl 4-(2-formyl-4-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylate

1017782-93-2
17 suppliers
inquiry