3-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid synthesis

4synthesis methods

Product Name:3-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazole-5-carboxylic acid
CAS Number:109888-65-5
Molecular formula:C11H8F3NO3
Molecular Weight:259.18

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 81 percent / triethylamine; MgSO₄ / toluene / 20 °C
2: 87 percent / aq. sodium hydroxide / aq. ethanol / Heating

References:

Golebiewski;Gucma [Journal of Heterocyclic Chemistry,2006,vol. 43,# 2,p. 509 - 513]

455-19-6 Synthesis

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