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1H-Indole-2-carboxylic acid, 1-acetyl-2,3-dihydro-, Methyl ester, (2S)- synthesis

10synthesis methods
L-Phenylalanine, N-acetyl-2-bromo-, methyl ester

194724-02-2
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1H-Indole-2-carboxylic acid, 1-acetyl-2,3-dihydro-, Methyl ester, (2S)-

110592-39-7
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-

Yield:110592-39-7 98%

Reaction Conditions:

with tris(dibenzylideneacetone)dipalladium (0);caesium carbonate;tris-(o-tolyl)phosphine in toluene at 100; for 15 h;

References:

Wagaw, Seble;Rennels, Roger A.;Buchwald, Stephen L. [Journal of the American Chemical Society,1997,vol. 119,# 36,p. 8451 - 8458]