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110826-01-2

(1R,2R)-2-(2-methoxyphenyl)cyclopropane-1-carboxylic acid synthesis

5synthesis methods
Cyclopropanecarboxylic acid, 2-(2-methoxyphenyl)-, methyl ester, (1R,2R)-rel-

110826-41-0
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(1R,2R)-2-(2-methoxyphenyl)cyclopropane-1-carboxylic acid

110826-01-2
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Yield:110826-01-2 92%

Reaction Conditions:

with sodium hydroxide in methanol;

References:

Arvidsson;Johansson;Hacksell;Nilsson;Svensson;Hjorth;Magnusson;Carlsson;Lindberg;Andersson;Sanchez;Wikstrom;Sundell [Journal of Medicinal Chemistry,1988,vol. 31,# 1,p. 92 - 99]