[4-[[5-Chloro-4-(MethylaMino)-2-pyriMidinyl]aMino]-3-Methoxyphenyl]-4-MorpholinylMethanone synthesis
- Product Name:[4-[[5-Chloro-4-(MethylaMino)-2-pyriMidinyl]aMino]-3-Methoxyphenyl]-4-MorpholinylMethanone
- CAS Number:1351758-81-0
- Molecular formula:C17H20ClN5O3
- Molecular Weight:377.83
5081-36-7
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$6.00/1g
1351758-81-0
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$26.00/1mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: thionyl chloride / toluene / 2 h / 120 °C / Inert atmosphere
1.2: 1 h / 0 - 20 °C
2.1: 10% Pd/C / methanol / 12 h / 20 °C / Inert atmosphere
3.1: trifluoroacetic acid / iso-butanol / 12 h / 110 °C / Inert atmosphere
References:
Choi, Hwan Geun;Zhang, Jinwei;Deng, Xianming;Hatcher, John M.;Patricelli, Matthew P.;Zhao, Zheng;Alessi, Dario R.;Gray, Nathanael S. [ACS Medicinal Chemistry Letters,2012,vol. 3,# 8,p. 658 - 662]
2486-69-3
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$8.00/1g
1351758-81-0
74 suppliers
$26.00/1mg
761440-55-5
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1351758-81-0
74 suppliers
$26.00/1mg