(δR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-δ,7a-dimethyl-1H-indene-1-pentanoic Acid Methyl Ester synthesis
- Product Name:(δR,1R,3aR,4S,7aR)-Octahydro-4-hydroxy-δ,7a-dimethyl-1H-indene-1-pentanoic Acid Methyl Ester
- CAS Number:135359-40-9
- Molecular formula:C17H30O3
- Molecular Weight:282.4183
![(1R,3aR,4S,7aR)-Octahydro-1-[(1S)-2-iodo-1-methylethyl]-7a-methyl-1H-inden-4-ol](/CAS2/GIF/116535-65-0.gif)
116535-65-0
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$1230.00/500mg
292638-85-8
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135359-40-9
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$165.00/25mg
Yield:135359-40-9 93%
Reaction Conditions:
Stage #1: acrylic acid methyl esterwith pyridine;nickel(II) chloride hexahydrate;zinc at 60; for 1 h;Inert atmosphere;
Stage #2: (1R,3aR,4S,7aR)-octahydro-1-[(S)-1-iodopropan-2-yl]-7a-methyl-1H-inden-4-olwith pyridine at 0; for 2 h;Inert atmosphere;
References:
WO2016/103722,2016,A1 Location in patent:Paragraph 0102
64190-52-9
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$180.00/50mg
135359-40-9
8 suppliers
$165.00/25mg