TERT-BUTYL (3-AMINO-1,1,1-TRIFLUOROPROPAN-2-YL)CARBAMATE synthesis
- Product Name:TERT-BUTYL (3-AMINO-1,1,1-TRIFLUOROPROPAN-2-YL)CARBAMATE
- CAS Number:1429913-34-7
- Molecular formula:C8H15F3N2O2
- Molecular Weight:228.2121
![Carbamic acid, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-3,3,3-trifluoropropyl]-, phenylmethyl ester](/CAS/20200119/GIF/1429913-40-5.gif)
1429913-40-5
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1429913-34-7
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Yield:1429913-34-7 55%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol at 20; for 16 h;Sealed tube;Inert atmosphere;
References:
Ellis, J. Michael;Altman, Michael D.;Bass, Alan;Butcher, John W.;Byford, Alan J.;Donofrio, Anthony;Galloway, Sheila;Haidle, Andrew M.;Jewell, James;Kelly, Nancy;Leccese, Erica K.;Lee, Sandra;Maddess, Matthew;Miller, J. Richard;Moy, Lily Y.;Osimboni, Ekundayo;Otte, Ryan D.;Reddy, M. Vijay;Spencer, Kerrie;Sun, Binyuan;Vincent, Stella H.;Ward, Gwendolyn J.;Woo, Grace H. C.;Yang, Chiming;Houshyar, Hani;Northrup, Alan B. [Journal of Medicinal Chemistry,2015,vol. 58,# 4,p. 1929 - 1939] Location in patent:supporting information