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N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine synthesis
1synthesis methods
- Product Name:N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
- CAS Number:1438071-12-5
- Molecular formula:C20H18Cl2N2O2S
- Molecular Weight:421.34
Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: 0.08 h / 20 °C
1.2: 16 h / 20 °C
2.1: sodium tris(acetoxy)borohydride / 24 h / 20 °C
References:
Trump, Ryan P.;Bresciani, Stefano;Cooper, Anthony W. J.;Tellam, James P.;Wojno, Justyna;Blaikley, John;Orband-Miller, Lisa A.;Kashatus, Jennifer A.;Boudjelal, Mohamed;Dawson, Helen C.;Loudon, Andrew;Ray, David;Grant, Daniel;Farrow, Stuart N.;Willson, Timothy M.;Tomkinson, Nicholas C. O. [Journal of Medicinal Chemistry,2013,vol. 56,# 11,p. 4729 - 4737]