(+)-(3R,4S)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE synthesis

5synthesis methods

Product Name:(+)-(3R,4S)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE
CAS Number:145678-87-1
Molecular formula:C13H19NO
Molecular Weight:205.3

4629-80-5 Synthesis

4629-80-5
209 suppliers
$7.00/5g

(+)-(3R,4S)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE

145678-87-1
28 suppliers
$245.00/25mg

Yield:-

Steps:

Multi-step reaction with 6 steps
1.1: tetrahydrofuran
2.1: ethyl acetate
2.2: (+)-diethyl ditoluyltartrate
3.1: decahydronaphthalene / Heating
4.1: n-BuLi
5.1: phenyl chloroformate
6.1: HBr; AcOH

References:

Thomas, James B.;Atkinson, Robert N.;Vinson, N. Ariane;Catanzaro, Jennifer L.;Perretta, Carin L.;Fix, Scott E.;Mascarella, S. Wayne;Rothman, Richard B.;Xu, Heng;Dersch, Christina M.;Cantrell, Buddy E.;Zimmerman, Dennis M.;Carroll, F. Ivy [Journal of Medicinal Chemistry,2003,vol. 46,# 14,p. 3127 - 3137]

4-Piperidinol, 1,3-diMethyl-4-[3-(1-Methylethoxy)phenyl]-

145340-44-9
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145678-87-1
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References

Pyridine, 1,2,3,6-tetrahydro-1,3-diMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3S)-

444904-02-3
4 suppliers
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145678-87-1
28 suppliers
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References

Piperidine, 1,3,4-triMethyl-4-[3-(1-Methylethoxy)phenyl]-, (3S,4S)-

223424-24-6
3 suppliers
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145678-87-1
28 suppliers
$245.00/25mg

References

131738-73-3
144 suppliers
$30.00/1g

145678-87-1
28 suppliers
$245.00/25mg

References