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ChemicalBook CAS DataBase List (R)-(-)-N-NEOPENTYL-1-PHENYL-2-(1-PIPERIDINO)ETHYLAMINE

(R)-(-)-N-NEOPENTYL-1-PHENYL-2-(1-PIPERIDINO)ETHYLAMINE synthesis

6synthesis methods
-

Yield:153837-28-6 85%

Reaction Conditions:

Stage #1: (R)-1-phenyl-2-(1-piperidinyl)ethanolwith methanesulfonyl chloride;triethylamine in diethyl ether; for 0.5 h;
Stage #2: 2.2-dimethylpropylaminewith water;triethylamine in diethyl ether at 20; for 16 h;

References:

Curthbertson;O'Brien;Towers [Synthesis,2001,# 5,p. 693 - 695]

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