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172734-70-2

Methanone, [(3S)-3-(3,4-dichlorophenyl)-3-(3-hydroxypropyl)-1-piperidinyl]phenyl- synthesis

4synthesis methods
Piperidine, 3-(3,4-dichlorophenyl)-3-(2-propen-1-yl)-, (3S)-

193755-91-8
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Methanone, [(3S)-3-(3,4-dichlorophenyl)-3-(3-hydroxypropyl)-1-piperidinyl]phenyl-

172734-70-2
6 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydroxide; dihydrogen peroxide / tetrahydrofuran; water / 2 h / 0 °C
2: triethylamine / dichloromethane / 0 - 20 °C

References:

Inukai, Tomoaki;Kano, Taichi;Maruoka, Keiji [Angewandte Chemie - International Edition,2020,vol. 59,# 6,p. 2211 - 2214][Angew. Chem.,2020,vol. 132,p. 2231 - 2234,4]