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ChemicalBook CAS DataBase List 4,5-Dichloro-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one
173206-13-8

4,5-Dichloro-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one synthesis

2synthesis methods
-

Yield:173206-13-8 87%

Reaction Conditions:

with toluene-4-sulfonic acid in tetrahydrofuran;Heating;

References:

Dyck, Brian;Markison, Stacy;Zhao, Liren;Tamiya, Junko;Grey, Jonathan;Rowbottom, Martin W.;Zhang, Mingzhu;Vickers, Troy;Sorensen, Katie;Norton, Christi;Wen, Jenny;Heise, Christopher E.;Saunders, John;Conlon, Paul;Madan, Ajay;Schwarz, David;Goodfellow, Val S. [Journal of Medicinal Chemistry,2006,vol. 49,# 13,p. 3753 - 3756]