ChemicalBook CAS DataBase List 1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid

1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid synthesis

1synthesis methods

Product Name:1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid
CAS Number:186203-08-7
Molecular formula:C13H14F3NO2
Molecular Weight:273.25

381-98-6 Synthesis

381-98-6
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$6.00/1g

93102-05-7 Synthesis

N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine

93102-05-7
313 suppliers
$6.00/1g

1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid

186203-08-7
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Yield:186203-08-7 96%

Reaction Conditions:

with trifluoroacetic acid in dichloromethane;

References:

Fukui, Hideto;Shibata, Tetsuo;Naito, Takanobu;Nakano, Jun;Maejima, Tetsuro;Senda, Hisato;Iwatani, Wakao;Tatsumi, Yoshiyuki;Suda, Masahiro;Arika, Tadashi [Bioorganic and Medicinal Chemistry Letters,1998,vol. 8,# 20,p. 2833 - 2838]

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