N-{[5-(4-Nitrophenyl)furan-2-yl]methylidene}hydroxylamine synthesis

Yield:19934-32-8 85%

Reaction Conditions:

with piperidine;hydroxyamino hydrochloride in ethanol; for 0.5 h;Reflux;

Steps:

General procedure for the preparation of oximes

General procedure: Equimolecular quantities (5 mmol) of 5-arylfuran-2-carbaldehyde and hydroxylamine hydrochloride were refluxed in ethanol for 30 min in the presence of 2, 3 drops of piperidine as a catalyst. On cooling precipitates were formed which were filtered, dried and recrytallized from ethanol.

References:

Aslam, Samina;Khakwani, Samia;Jnazeer, Areesha;Shahi, Mehrzadi Jnoureen;Yaqoob, Asma;Shafiq, Hamna;Manazer, Rafia;Nasim, Faizul Hassan;Khan, Misbahul Ain [Asian Journal of Chemistry,2016,vol. 28,# 6,p. 1210 - 1214]