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1H-Indole-3-carboxaMide, N-(2-chlorophenyl)- synthesis

1synthesis methods
-

Yield:61788-27-0 26%

Reaction Conditions:

with 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;N-ethyl-N,N-diisopropylamine;N,N-dimethyl-formamide in dichloromethane at 20;

References:

Qiao, Lixin;Choi, Sungwoon;Case, April;Gainer, Thomas G.;Seyb, Kathleen;Glicksman, Marcie A.;Lo, Donald C.;Stein, Ross L.;Cuny, Gregory D. [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 21,p. 6122 - 6126] Location in patent:supporting information; experimental part