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1368594-82-4

1H-Indole, 7-fluoro-1,3-dimethyl- synthesis

2synthesis methods
2368-80-1 Synthesis
2-Fluorophenylhydrazine

2368-80-1
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1H-Indole, 7-fluoro-1,3-dimethyl-

1368594-82-4
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-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: dichloromethane / 0.17 h / 20 °C
2.1: zinc(II) chloride / para-xylene / 160 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere

References:

Su, Yi-Ming;Hou, Yu;Yin, Feng;Xu, Yue-Ming;Li, Yan;Zheng, Xiaoqi;Wang, Xi-Sheng [Organic Letters,2014,vol. 16,# 11,p. 2958 - 2961]