1H-Pyrrole-2-carboxamide,N-methoxy-N-methyl-(9CI) synthesis
4synthesis methods
- Product Name:1H-Pyrrole-2-carboxamide,N-methoxy-N-methyl-(9CI)
- CAS Number:368211-06-7
- Molecular formula:C7H10N2O2
- Molecular Weight:154.17
Yield:368211-06-7 97%
Reaction Conditions:
Stage #1: pyrrolewith bis(trichloromethyl) carbonate;N,N-dimethyl-aniline in toluene at 0 - 20; for 2.33333 h;Inert atmosphere;
Stage #2: N,O-dimethylhydroxylamine*hydrochloridewith triethylamine in toluene at 20; for 0.5 h;Inert atmosphere;
References:
Borrero, Nicholas V.;Aponick, Aaron [Journal of Organic Chemistry,2012,vol. 77,# 19,p. 8410 - 8416,7]
