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ChemicalBook CAS DataBase List (1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE
1213137-26-8

(1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE synthesis

3synthesis methods
(αS)-3-Methoxy-N-(4-methoxyphenyl)-α-(trifluoromethyl)benzenemethanamine

1334287-98-7
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(1S)-2,2,2-TRIFLUORO-1-(3-METHOXYPHENYL)ETHYLAMINE

1213137-26-8
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Yield:1213137-26-8 99%

Reaction Conditions:

with sulfuric acid;periodic acid in water;acetonitrile at 20; for 24 h;optical yield given as %ee;

References:

Henseler, Alexander;Kato, Masanori;Mori, Keiji;Akiyama, Takahiko [Angewandte Chemie - International Edition,2011,vol. 50,# 35,p. 8180 - 8183] Location in patent:supporting information; experimental part