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297765-48-1

(1S)-2-azido-1-(4-fluorophenyl)ethan-1-ol synthesis

2synthesis methods
2-azido-1-(4-fluorophenyl)ethan-1-one

118887-70-0
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(1S)-2-azido-1-(4-fluorophenyl)ethan-1-ol

297765-48-1
2 suppliers
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Yield:> 99 % ee

Reaction Conditions:

with alcohol dehydrogenase KRED-NADH-110;magnesium sulfate in aq. phosphate buffer;isopropyl alcohol at 30; pH=7; for 20 h;Autoclave;Green chemistry;Enzymatic reaction;stereoselective reaction;

References:

Schrittwieser, Joerg H.;Coccia, Francesca;Kara, Selin;Grischek, Barbara;Kroutil, Wolfgang;D'Alessandro, Nicola;Hollmann, Frank [Green Chemistry,2013,vol. 15,# 12,p. 3318 - 3331] Location in patent:supporting information