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ChemicalBook CAS DataBase List 2,2',6,6'-tetramethylbenzhydryl alcohol

2,2',6,6'-tetramethylbenzhydryl alcohol synthesis

5synthesis methods
-

Yield:22004-65-5 85%

Reaction Conditions:

Stage #1: 2-Bromo-m-xylenewith magnesium in tetrahydrofuran at 20;Reflux;
Stage #2: 2,6-dimethylbenzaldehyde in tetrahydrofuran at 0 - 20;
Stage #3: with water;sodium carbonate in tetrahydrofuran;

References:

Yu, Jung-Yi;Kuwano, Ryoichi [Organic Letters,2008,vol. 10,# 5,p. 973 - 976] Location in patent:supporting information; experimental part

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