2,2-DIMETHYL-2,3-DIHYDROBENZOFURAN-3-OL synthesis

Yield:103324-02-3 77%

Reaction Conditions:

with sodium tetrahydroborate in methanol at 0 - 20; for 3 h;

References:

Papillon, Julien P. N.;Adams, Christopher M.;Hu, Qi-Ying;Lou, Changgang;Singh, Alok K.;Zhang, Chun;Carvalho, Jose;Rajan, Srinivan;Amaral, Adam;Beil, Michael E.;Fu, Fumin;Gangl, Eric;Hu, Chii-Whei;Jeng, Arco Y.;LaSala, Daniel;Liang, Guiqing;Logman, Michael;Maniara, Wieslawa M.;Rigel, Dean F.;Smith, Sherri A.;Ksander, Gary M. [Journal of Medicinal Chemistry,2015,vol. 58,# 11,p. 4749 - 4770] Location in patent:supporting information