2,2-DiMethyl-3-oxocyclobutanecarboxylic acid synthesis
- Product Name:2,2-DiMethyl-3-oxocyclobutanecarboxylic acid
- CAS Number:3183-43-5
- Molecular formula:C7H10O3
- Molecular Weight:142.15
78685-51-5
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$200.00/50mg
3183-43-5
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$60.00/1g
Yield:3183-43-5 91%
Reaction Conditions:
Stage #1: 2,2-dimethyl-3-oxo-cyclobutanecarboxylic acid methyl esterwith water;lithium hydroxide in tetrahydrofuran at 23; for 18 h;Inert atmosphere;
Stage #2: with hydrogenchloride in tetrahydrofuran at 0; for 0.0833333 h;
References:
O'Brien, Jeannette M.;Kingsbury, Jason S. [Journal of Organic Chemistry,2011,vol. 76,# 6,p. 1662 - 1672] Location in patent:experimental part