2,2-DIMETHYLTETRAHYDROFURAN synthesis
- Product Name:2,2-DIMETHYLTETRAHYDROFURAN
- CAS Number:1003-17-4
- Molecular formula:C6H12O
- Molecular Weight:100.16
22508-64-1
46 suppliers
$45.00/10mg
1003-17-4
41 suppliers
$857.41/5G
Yield:1003-17-4 96%
Reaction Conditions:
with calcium(II) bis(trifluoromethanesulfonyl)imide;tert-butylammonium hexafluorophosphate(V) in dichloromethane at 20; for 2 h;
Steps:
General procedure for the Hydroalkoxylation
General procedure: The alcohol (0.25 mmol) is dissolved in 2 ml of dichloromethane. Bu4NPF6 (5 mol%) and Ca(NTf2)2 (5 mol%) are added at indicated temperature and stirred until conversion of the alcohol is complete (monitored by TLC and/or GC). For the isolation of the product, 5 mL sat. NaHCO3-solution is added, the aqueous phase extracted with dichloromethane, the combined organic phases dried over Na2SO4 and concentrated in vacuo. The crude product is purified by column chromatography.
References:
Kena Diba, Anastasie;Begouin, Jeanne-Marie;Niggemann, Meike [Tetrahedron Letters,2012,vol. 53,# 49,p. 6629 - 6632,4] Location in patent:supporting information Kena Diba, Anastasie;Begouin, Jeanne-Marie;Niggemann, Meike [Tetrahedron Letters,2012,vol. 53,# 49,p. 6629 - 6632] Location in patent:supporting information
5891-21-4
370 suppliers
$5.00/5g
676-58-4
296 suppliers
$15.00/25ml
1003-17-4
41 suppliers
$857.41/5G
5891-21-4
370 suppliers
$5.00/5g
917-54-4
180 suppliers
$44.39/50ml
1003-17-4
41 suppliers
$857.41/5G
25163-50-2
1 suppliers
inquiry
1003-17-4
41 suppliers
$857.41/5G