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ChemicalBook CAS DataBase List 2,3,6-TRIFLUOROPHENYLACETONITRILE

2,3,6-TRIFLUOROPHENYLACETONITRILE synthesis

1synthesis methods
773837-37-9 Synthesis
sodium:cyanide

773837-37-9
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Yield: 79%

Reaction Conditions:

in ethanol;waterReflux;

References:

Mandal, Mihirbaran;Wu, Yusheng;Misiaszek, Jeffrey;Li, Guoqing;Buevich, Alexei;Caldwell, John P.;Liu, Xiaoxiang;Mazzola, Robert D.;Orth, Peter;Strickland, Corey;Voigt, Johannes;Wang, Hongwu;Zhu, Zhaoning;Chen, Xia;Grzelak, Michael;Hyde, Lynn A.;Kuvelkar, Reshma;Leach, Prescott T.;Terracina, Giuseppe;Zhang, Lili;Zhang, Qi;Michener, Maria S.;Smith, Brad;Cox, Kathleen;Grotz, Diane;Favreau, Leonard;Mitra, Kaushik;Kazakevich, Irina;McKittrick, Brian A.;Greenlee, William;Kennedy, Matthew E.;Parker, Eric M.;Cumming, Jared N.;Stamford, Andrew W. [Journal of Medicinal Chemistry,2016,vol. 59,# 7,p. 3231 - 3248]

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