2,4,5-TRIHYDROXYPHENYLALANINE synthesis

9synthesis methods

Yield:-

Steps:

Multi-step reaction with 4 steps
1: LiAlH₄ / tetrahydrofuran
2: PBr₃ / CCl₄
3: NaH
4: (i) H₂, Pd-C, EtOH, aq. HCl, (ii) (heating)

References:

Ong,H.H. et al. [Journal of Medicinal Chemistry,1969,vol. 12,# 3,p. 458 - 461]

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