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ChemicalBook CAS DataBase List 2,4-DIFLUOROPHENYLBUTYRIC ACID

2,4-DIFLUOROPHENYLBUTYRIC ACID synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: (Ph)2PCl2, Et3N / dimethylformamide / 6 h / 85 °C
2: H2 / 10percent Pd/C / ethyl acetate / 3102.9 Torr
3: 6N aq. H2CrO4 / acetone / 20 °C

References:

Martinez [Tetrahedron Asymmetry,1995,vol. 6,# 7,p. 1491 - 1494]

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