2-(4-METHYLPIPERAZINO)-4(3H)-QUINAZOLINONE synthesis
- Product Name:2-(4-METHYLPIPERAZINO)-4(3H)-QUINAZOLINONE
- CAS Number:16822-65-4
- Molecular formula:C13H16N4O
- Molecular Weight:244.29
118-92-3
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: thionyl chloride / 2 h / Reflux; Inert atmosphere
1.2: 0.75 h / 20 °C / Inert atmosphere
2.1: sodium hydroxide / water; methanol / 1 h / 20 °C / Inert atmosphere
3.1: 0.5 h / 160 °C / Microwave irradiation; Inert atmosphere
References:
Verheij, Mark H. P.;Thompson, Andrew J.;Van Muijlwijk-Koezen, Jacqueline E.;Lummis, Sarah C. R.;Leurs, Rob;De Esch, Iwan J. P. [Journal of Medicinal Chemistry,2012,vol. 55,# 20,p. 8603 - 8614]
13906-09-7
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$45.00/250mg
16822-65-4
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