2-(6-Bromo-3-pyridyl)-2-methylpropanenitrile synthesis

1synthesis methods

Yield:850197-45-4 19 %

Reaction Conditions:

Stage #1: 2-(6-bromopyridin-3-yl)acetonitrilewith sodium hydride in tetrahydrofuran at 0 - 20;
Stage #2: methyl iodide in tetrahydrofuran at 20;

References:

WO2023/11456,2023,A1 Location in patent:Page/Page column 36; 37

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