2,6-diaminonaphthalene synthesis
- Product Name:2,6-diaminonaphthalene
- CAS Number:2243-67-6
- Molecular formula:C10H10N2
- Molecular Weight:158.2
1312611-11-2
1 suppliers
inquiry
2243-67-6
52 suppliers
inquiry
Yield:2243-67-6 46%
Reaction Conditions:
Stage #1: C12H6N6O2with sulfuric acid at 0 - 20; for 2 h;
Stage #2: with sodium hydroxide in water;Cooling with ice;
Steps:
VII.VII-III.VII-L
General Procedure VII-LCompound VII-IIIB (1.5 g, 5.64 mmol) was added into 45 mL of conc. H2SO4 at 0° C. portion wise. After addition, the reaction solution was stirred at r.t. for 2 hrs. The solution was poured into ice water (20 mL) slowly and made alkaline by addition of aq. NaOH (50%). The mixture was extracted with EtOAc (100 mL×3). The combined organic layers were washed with brine, dried over anhydrous Na2SO4, and concentrated in vacuo to give naphthalene-2,6-diamine (VII-IIIC) (411 mg, yield 46%), which was used directly in next step without further purification.
References:
US2011/152246,2011,A1 Location in patent:Page/Page column 260
3230-35-1
51 suppliers
inquiry
2243-67-6
52 suppliers
inquiry
581-43-1
296 suppliers
$6.00/250mg
2243-67-6
52 suppliers
inquiry
1141-38-4
257 suppliers
$5.00/250mg
2243-67-6
52 suppliers
inquiry
2351-36-2
57 suppliers
inquiry
2243-67-6
52 suppliers
inquiry