2,7-Diazaspiro[3.5]nonane, 7-Methyl- synthesis
- Product Name:2,7-Diazaspiro[3.5]nonane, 7-Methyl-
- CAS Number:135380-50-6
- Molecular formula:C8H16N2
- Molecular Weight:140.23
![2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester](/CAS/GIF/1093066-77-3.gif)
1093066-77-3
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135380-50-6
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Yield:-
Reaction Conditions:
with trifluoroacetic acid in dichloromethane at 0 - 20; for 3 h;
Steps:
A26 Preparation of intermediate 190
Intermediate 189 was dissolved in DCM (15 mL) and cooled to 0°C. The suspension was treated with TFA (3.1 mL) dropwise. The mixture was stirred at room temperature for 3 hours The solvents were evaporated to dryness and the product was triturated with ether to give crude intermediate 190 (0.273 g, 100% yield), which was used a such without further purification.
References:
WO2017/153186,2017,A1 Location in patent:Page/Page column 132
20691-92-3
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135380-50-6
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157736-50-0
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135380-50-6
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![N-BOC-7-BENZYL-2,7-DIAZASPIRO[3.5]NONANE](/CAS/GIF/929301-99-5.gif)
929301-99-5
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135380-50-6
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$496.07/5MG
![2-(TERT-BUTOXYCARBONYL)-2,7-DIAZASPIRO[3.5]NONANE HYDROCHLORIDE](/CAS/GIF/929302-18-1.gif)
929302-18-1
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$45.00/100mg
135380-50-6
20 suppliers
$496.07/5MG