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ChemicalBook CAS DataBase List 7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-amino-, 1,1-dimethylethyl ester

7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-amino-, 1,1-dimethylethyl ester synthesis

6synthesis methods
240401-28-9 Synthesis
7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester

240401-28-9
77 suppliers
$45.00/50mg

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Yield:-

Steps:

Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 1 h / -10 - 20 °C
2: sodium azide / N,N-dimethyl-formamide / 90 °C
3: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C

References:

Guangzhou Hengnuokang Pharmaceutical Technology Co., Ltd.;Zhang Jiancun;Lin Cai;Zou Qingan CN108456208, 2018, A