2-(Benzylamino)-4-chlorobenzonitrile synthesis
1synthesis methods
- Product Name:2-(Benzylamino)-4-chlorobenzonitrile
- CAS Number:296259-54-6
- Molecular formula:C14H11ClN2
- Molecular Weight:242.7
Yield: 78%
Reaction Conditions:
Stage #1:2-amino-4-chlorobenzonitrile;benzaldehyde with acetic acid at 20; for 1 h;
Stage #2: with sodium tetrahydroborate at 0; for 0.166667 h;
References:
Zhao, Huai-Bo;Hou, Zhong-Wei;Liu, Zhan-Jiang;Zhou, Ze-Feng;Song, Jinshuai;Xu, Hai-Chao [Angewandte Chemie - International Edition,2017,vol. 56,# 2,p. 587 - 590][Angew. Chem.,2017,vol. 129,# 2,p. 602 - 605] Location in patent:supporting information