2-bromo-[1,2,4]triazolo[1,5-a]pyrazine synthesis
- Product Name:2-bromo-[1,2,4]triazolo[1,5-a]pyrazine
- CAS Number:1359702-68-3
- Molecular formula:C5H3BrN4
- Molecular Weight:199.01
![[1,2,4]Triazolo[1,5-a]pyrazin-2-amine](/CAS/20180703/GIF/88002-33-9.gif)
88002-33-9
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$11.00/100mg
1359702-68-3
35 suppliers
$180.00/100mg
Yield:1359702-68-3 61.1%
Reaction Conditions:
Stage #1: [1,2,4]triazolo[1,5-a]pyrazin-2-aminewith hydrogen bromide;acetic acid;sodium nitrite in water at 0; for 2 h;
Stage #2: with copper(I) bromide in water; for 8 h;Reflux;
References:
Cao, Xufeng;Sun, Zhaoshuan;Cao, Yongbing;Wang, Ruilian;Cai, Tongkai;Chu, Wenjing;Hu, Wenhao;Yang, Yushe [Journal of Medicinal Chemistry,2014,vol. 57,# 9,p. 3687 - 3706] Location in patent:supporting information
![Carbamic acid, N-[(2-pyrazinylamino)thioxomethyl]-, ethyl ester](/CAS/20210305/GIF/56406-73-6.gif)
56406-73-6
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1359702-68-3
35 suppliers
$180.00/100mg