2-BROMO-6,7-DIHYDRO-1H-INDOL-4(5H)-ONE synthesis

Yield:27784-79-8 83%

Reaction Conditions:

with 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione in N,N-dimethyl-formamide at -60; for 0.166667 h;

References:

Pettus, Liping H.;Andrews, Kristin L.;Booker, Shon K.;Chen, Jie;Cee, Victor J.;Chavez, Frank;Chen, Yuping;Eastwood, Heather;Guerrero, Nadia;Herberich, Bradley;Hickman, Dean;Lanman, Brian A.;Laszlo, Jimmy;Lee, Matthew R.;Lipford, J. Russell;Mattson, Bethany;Mohr, Christopher;Nguyen, Yen;Norman, Mark H.;Powers, David;Reed, Anthony B.;Rex, Karen;Sastri, Christine;Tamayo, Nuria;Wang, Paul;Winston, Jeffrey T.;Wu, Bin;Wu, Tian;Wurz, Ryan P.;Xu, Yang;Zhou, Yihong;Tasker, Andrew S.;Wang, Hui-Ling [Journal of Medicinal Chemistry,2016,vol. 59,# 13,p. 6407 - 6430]