2-bromo-8-iododibenzofuran synthesis
- Product Name:2-bromo-8-iododibenzofuran
- CAS Number:916435-41-1
- Molecular formula:C12H6BrIO
- Molecular Weight:372.98
5408-56-0
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916435-41-1
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$60.00/5mg
Yield: 62.2%
Reaction Conditions:
with bromine;acetic acid at 50 - 66; for 16 h;
Steps:
2 Synthesis of Exemplified Compound 2-1
10 g (0.034 mol) of Exemplified Compound 3-1 and 200 ml of acetic acid were mixed, and 10.9 g (× 2 mol) of bromine was added dropwise in the vicinity of 50 ° C. over 10 minutes,And the mixture was further stirred for 16 hours. (Internal temperature 65 to 66 ° C.) After stirring at room temperature for 1 hour, filtration under reduced pressure was carried out.The obtained crystals were added to a THF / methanol mixture and the suspension was refluxed for 30 minutes. After stirring at room temperature for 1 hour, filtration under reduced pressure gave Exemplified Compound 2-1, 7.9 g. (Yield 62.2%) Identification of each compound in the examples was carried out by MASS and NMR spectra, and it was confirmed that they were the target compound. Exemplary compounds according to other general formulas [2] and [5] can also be synthesized according to the above-mentioned method.
References:
Konica Minolta Co., Ltd.;Sugita, Shuichi;Kato, Eisaku JP5968214, 2016, B2 Location in patent:Paragraph 0055-0057
86-76-0
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916435-41-1
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132-64-9
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916435-41-1
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$60.00/5mg