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2-bromo-N-(2-chlorobenzyl)butanamide synthesis

1synthesis methods
-

Yield:28046-14-2 82%

Reaction Conditions:

with 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide;triethylamine in dichloromethane at -17 - 20; for 1.5 h;Inert atmosphere;

References:

Gryz?o, Beata;Zar?ba, Paula;Malawska, Katarzyna;Mazur, Gabriela;Rapacz, Anna;??tka, Kamil;H?fner, Georg C.;Latacz, Gniewomir;Bajda, Marek;Sa?at, Kinga;Wanner, Klaus T.;Malawska, Barbara;Kulig, Katarzyna [ACS Chemical Neuroscience,2021,vol. 12,# 16,p. 3073 - 3100]